Faculty
kausik.bhattacharyya@mitwpu.edu.in Bio
Dr. Kausik Bhattacharyya is an Assistant Professor at the Department of Biosciences and Technology (DoBT) and Revvity – MIT-WPU Centre of Excellence for Bioimaging Technologies and Innovation. Serving additionally as a Departmental Placement coordinator for the department of Biosciences and Technology, Dr Kausik has more than 12 years of research experience in Infectious Disease biology, Microbiology, Genomics and Bioinformatics and 7 years of teaching experience. He has completed his Ph.D. from Department of Biomedical Sciences (ACBR), University of Delhi. During his Ph.D., he has demonstrated how genomic sequence and novel genomic variations can have functional significance in Multi-Drug Resistant (MDR) clinical isolates of M. tuberculosis through Bioinformatics and Experimental approaches, including altering protein 3D structure, causing drug resistance, altering host-pathogen interactions, Molecular mimicry, and Evasion of Immune responses. Before joining Ph.D., he worked as a junior Team Mentor and Project Fellow in the area of drug discovery against Tuberculosis (OSDD), a CSIR-led Team India Consortium with global participation. (https://en.wikipedia.org/wiki/Open_Source_Drug_Discovery) at Institute of Genomics and Integrative Biology (IGIB), Delhi and Institute of Microbial Technology (IMTECH), Chandigarh.
He has contributed to the development of India's first consolidated Genetic Disease Database (https://en.wikipedia.org/wiki/Indian_Genetic_Disease_Database) during his research at Indian Institute of Chemical biology (IICB), Kolkata. Dr. Kausik has 3 years of Post-Doctoral research experience at Indian Institute of Technology (IIT) Delhi, Indian Institute of Science (IISc), Bangalore and SSSIHL, Puttaparthi where he worked on habitat-specific bacterial behaviour, bacterial gene expression and Anti-Microbial Resistance (AMR).
Dr Kausik trained students in different Bioinformatics and Molecular biology workshops. Dr Kausik has worked with different Industry experts during his research journey. Currently, Dr Kausik works in the amalgamation of both Bioinformatics as well as Experimental approaches in the area of Bacterial and Viral genomics.
Subjects Taught
1. Genomics and proteomics
2. Computational biology and Bioinformatics
3. Animal cell culture
4. Microbiology
Research Interests
Infectious diseases, Inter Microbial interaction, Habitat Specific bacterial interaction and behaviour, Microbiome, Bacterial and Viral genomics
Research Papers
1. Bhattacharyya K, Nemaysh V, Joon M, Pratap R, Varma-Basil M, Bose M, Brahmachari V. Correlation of drug resistance with single nucleotide variations through genome analysis and experimental validation in a multi-drug resistant clinical isolate of M. tuberculosis. BMC microbiology. 2020 Dec;20(1):1-14. [IF:4.465]
2. Bhattacharyya K, Bandopadhyay U, Singh A, Prakash A, Nemaysh V, Jain S, Varma- Basil M, Lynn AM, Bose M, Luthra PM, Natarajan K. Modulation of macrophage defense responses by Mycobacterial persistence protein MprA (Rv0981) in human THP-1 cells: effect of single amino acid variation on host-pathogen interactions. bioRxiv. 2020 Apr 28:2020-04.
3. Maini J, Pathak AK, Bhattacharyya K, Kumar N, Narang A, Jain N, Singh I, Dhingra V, Brahmachari V. Human PRE-PIK3C2B exhibits long-range intra-and inter-chromosomal interactions with genomic regions enriched in repressive marks. bioRxiv. 2020 Nov 11:2020- 11.
4. Jain S, Bhattacharyya K, Bakshi R, Narang A, Brahmachari V. Distinguishing between biochemical and cellular function: A re there peptide signatures for cellular function of proteins? Proteins: Structure, Function, and Bioinformatics. 2017 Apr;85(4):682-93. [IF: 4.088]
5. Bandyopadhyay U, Chadha A, Gupta P, Tiwari B, Bhattacharyya K, Popli S, Raman R, Brahamachari V, Singh Y, Malhotra P, Natarajan K. Suppression of Toll-like receptor 2–mediated proinflammatory responses by Mycobacterium tuberculosis protein Rv3529c. Journal of leukocyte biology. 2017 Nov;102(5):1249-59. [IF: 6.011]
6. Shrivastava K, Garima K, Narang A, Bhattacharyya K, Vishnoi E, Singh RK, Chaudhry A, Prasad R, Bose M, Varma-Basil M. Rv1458c: a new diagnostic marker for identification of Mycobacterium tuberculosis complex in a novel duplex PCR assay. Journal of medical microbiology. 2017 Mar;66(3):371-6. [IF: 3.196]
7. Vashisht R, Mondal AK, Jain A, Shah A, Vishnoi P, Priyadarshini P, Bhattacharyya K, et al. …Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis. PloS one. 2012 Jul 11;7(7):e39808. (Joint 1st Author) [IF:3.752]
8. Pradhan S, Sengupta M, Dutta A, Bhattacharyya K, Bag SK, Dutta C, Ray K. Indian genetic disease database. Nucleic acids research. 2010 Oct 30;39(suppl_1):D933-8. [Featured Article]. [IF: 19.16].
Books Published
Ghosh S, Matsuoka Y, Asai Y, Kitano H, Bhardwaj A, Scaria V, Vashisht R, Shah A, Mondal AK, Vishnoi P, Sonal K, Jain A, Priyadarshini P, Bhattacharyya K, Kumar V, Passi A, Pratibha Sharma P, Brahmachari S. Software platform for metabolic network reconstruction of Mycobacterium tuberculosis. Systems Biology of Tuberculosis. Springer, New York, 2013: pp 21–35. (Book Chapter)
Teaching Experience
7 years of Teaching Experience
Research Experience
12 years (IICB-Kolkata, CSIR-IGIB, Imtech Chandigarh, CSIR HQ, ACBR-DU, IITDelhi, SSSIHL, IISc Bangalore)
Linkedin Profile Link
https://www.linkedin.com/in/kausik-bhattacharyya/
Scopus ID Link
https://www.scopus.com/authid/detail.uri?authorId=55313145700
ORCID ID Link
https://orcid.org/0000-0002-4033-676X
Vidwan Profile Link
admissions@mitwpu.edu.in
