Academics

Faculty

Dr. Mukul Sacchit Godbole
Assistant Professor

Bio

Dr. Mukul S. Godbole currently serves as an Assistant Professor in the Dept. of Biosciences and Technology, MIT-WPU. Dr. Godbole is a cancer cell biologist. His doctoral work focused on elucidating the mechanism of action of progesterone in human breast cancer. The work performed at ACTREC–TMC identified an intricate genomic network that suppresses breast cancer cell migration and invasion in response to progesterone, independent of progesterone receptor expression. Dr. Godbole has published 11 research articles and reviews in peer-reviewed journals of international repute. Dr. Godbole’s research interests include breast cancer, steroid hormones and receptors, cancer cell biology, metastasis, and microbiomes. Dr. Godbole serves as a Guest Editor for the ‘Cancer and Microbiome’ and ‘Cancer Metastasis: Mechanisms and Treatment’ special issues of Cancer Reports. He is also the Editorial Board Member of Cancer Reports. Further, Dr. Godbole serves as an Early Career Reviewer for the Journal of Biological Chemistry. He also serves as a peer-reviewer for Cancer Reports, Clinical Breast Cancer, BBA–Reviews on Cancer, Experimental Cell Research, Heliyon, npj Biofilms and Microbiomes, Microbial Cell, Cellular Signalling, PLoS One, Frontiers in Cellular and Infection Microbiology, Gut Microbes Reports, and STAR Protocols. Moreover, he has previously worked as a Freelance Science Editor with Cactus Communications Pvt. Ltd. for three years and edited 410 manuscripts.

Subjects Taught

Cancer Biology, Animal Cell Culture, Biochemistry and Metabolism, Animal Physiology, Molecular and Cellular Biology, Recombinant DNA Technology, Immunology, Genomics, Biology for Engineers

Research Interests

breast cancer, steroid hormones and receptors, cancer cell biology, metastasis, and microbiomes

Research Papers

Naik A* and Godbole MS*. Elucidating the Intricate Roles of Gut and Breast Microbiomes in Breast Cancer Metastasis to the Bone. Cancer Reports (Hoboken) (2024). 7(8):e70005. (*corresponding author) (IF: 1.5; Q3)

Godbole MS*, Singh V. Deciphering the impacts of gut and tissue microbiome on human cancers. Cancer Reports (Hoboken) (2023). 6(11):e1924 (*corresponding author) (IF: 1.5; Q3).

Chakravorty G, Ahmad S, Godbole MS, Gupta S, Badwe RA, Dutt A. Deciphering the mechanisms of action of progesterone in breast cancer. Oncotarget (2023). 14:660–667. (IF: 3.765; Q2).

Chapadgaonkar SS, Bajpai SS, Godbole MS*. Gut microbiome influences incidence and outcomes of breast cancer by regulating levels and activity of steroid hormones in women. Cancer Reports (Hoboken) (2023). 6(11):e1847 (*corresponding author) (IF: 1.5; Q3).

Yadav N, Sunder R, Desai S, Dharavath B, Chandrani P, Godbole M, Dutt A. Progesterone modulates the DSCAM-AS1/miR-130a/ESR1 axis to suppress breast cancer metastasis. Breast Cancer Research (2022). 24(1):97. (IF: 6.1; Q1).

Sikder S, Kumari S, …, Godbole M, Chandrani P, Dutt A, Gopinath KS and Kundu TK. Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a. Oncotarget (2019). 10(64): 6855–6869. (IF: 3.765; Q2).

Godbole M, Togar T, Patel K, …, Dutt S, Gupta S, Badwe RA, Dutt A. Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1–NDRG1 axis in both PR-positive and -negative breast cancer cells. Journal of Biological Chemistry (2018). 293(50):19263–19276. (IF: 4.0; Q1).

Godbole M, Chandrani P, …, Gupta S, Badwe RA, Dutt A. miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells. Cancer Biology & Therapy (2017). 18(10): 801–805. (IF: 4.4; Q2).

Godbole M, Tiwary K, Badwe RA, Gupta S, Dutt A. Progesterone suppresses the invasion and migration of breast cancer cells irrespective of their progesterone receptor status – a short report. Cellular Oncology (Dordrecht) (2017). 40(4): 411–417. (IF: 4.9; Q1).

Upadhyay P, Nair S, Kaur E, Aich J, Dani P, Sethunath V, Gardi N, Chandrani P, Godbole M …, Gupta S, Dutt S, Dutt A. Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer. Oncotarget (2016). 2;7(31): 50437–50449. (IF: 3.765; Q2).

Ramteke MP, Patel KJ, Godbole M …, Prabhash K, Dutt A. CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons. F1000Research (2016) 4:160 (Q1).

Teaching Experience

7 Yrs

Industry Experience

3 Yrs

Research Experience

1 yrs

Linkedin Profile Link

www.linkedin.com/in/mukul-godbole-22526025b

Scopus ID Link

https://www.scopus.com/authid/detail.uri?authorId=57210650570

ORCID ID Link

https://orcid.org/0000-0003-0711-8696

Researcher ID Link

https://www.webofscience.com/wos/author/record/AAT-4330-2021

Vidwan Profile Link

https://vidwan.inflibnet.ac.in/profile/507610

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