Faculty
Bio
Dr. Meenakshi Iyer is an Assistant Professor in the Department of Biosciences and Technology. She has done her PhD in Bioinformatics from NCBS-TIFR, Bangalore. She has a joint postdoctoral experience from KAVI-ICR, University of Nairobi, Kenya and NCBS-TIFR. She has also worked as a Project Scientist in NCBS and as a Bioinformatics Consultant for Molecular Solutions Care Health, Bangalore. She has worked on big data analysis, genomics, transcriptomics, bacterial, viral, medicinal plant and cancer sample omics, protein sequence analysis and evolution, protein structural biology, in silico vaccine design and epitope prediction.
Research Interests
Big data analysis, genomics, transcriptomics, bacterial, viral, medicinal plant and cancer sample omics, protein sequence analysis and evolution, protein structural biology, in silico vaccine design and epitope prediction.
Research papers
1. Revisiting Myosin Families Through Large-scale Sequence Searches Leads to the Discovery of New Myosins. Pasha SN, Meenakshi I, Sowdhamini R. 2016, Evolutionary Bioinformatics, 12: 201–211. DOI: 10.4137/EBO.S39880
2. Draft Genome of Cissus quadrangularis to elucidate the Medicinal Values. Gandhimathi A, Margaret Sunitha S, Pritha Ghosh, Harini K, Subramanian Hariprasanna P, Iyer Meenakshi S. et. al. 2016, Herbal Medicine, 2, 1-7. DOI: 10.21767/2472-0151.10007
3. Genome-wide survey of remote homologues for protein domain superfamilies of known structure reveals unequal distribution across structural classes. Iyer, M.S., Joshi, A.G. & Sowdhamini, R., 2018. Molecular omics, 14(4), 266-280. DOI: 10.1039/C8MO00008E.
4. GenDiS database update with improved approach and features to recognise homologous sequences of protein domain superfamilies. Iyer, M.S., Bhargava, K., Pavalam, M., & Sowdhamini, R., 2019. Database, DOI: 10.1093/database/baz042
5. Genome-wide survey of protein structural domains and analysis of domain architectures. Iyer Meenakshi S., Adwait G. Joshi and, R. Sowdhamini, 2019. Journal of Biomolecular Structure & Dynamics: 10.1080/07391102.2019.1604468
6. The transcriptome enables the identification of candidate genes behind medicinal value of Drumstick tree (Moringa oleifera) Pasha SN, Shafi KM, Joshi AG, Meenakshi I et. al., 2019. Genomics. pii: S0888-7543(18)30690-6. doi: 10.1016/j.ygeno.2019.04.014
7. Dataset for the first combined transcriptome assembly of M. oleifera and functional annotation. Shafi KM, Joshi AG, Meenakshi I et. al., 2019. Data Brief.; 30:105416. doi:10.1016/j.dib.2020.105416
8. A knowledge-driven protocol for prediction of proteins of interest with an emphasis on biosynthetic pathways. Joshi AG, Harini K, Meenakshi I, et al. 2020. MethodsX. 7: 101053. doi:10.1016/j.mex.2020.101053
9. Corresponding author: Antimicrobial Resistance Profiling and Phylogenetic Analysis of Neisseria gonorrhoeae Clinical Isolates From Kenya in a Resource-Limited Setting. Juma M, Sankaradoss A, Ndombi R, Mwaura P, Damodar T, Nazir J, Pandit A, Khurana R, Masika M, Chirchir R, Gachie J, Krishna S, Sowdhamini R, Anzala O and Meenakshi IS* (2021) Front. Microbiol. 12:647565. doi: 10.3389/fmicb.2021.647565
10. Immune profile and responses of a novel dengue DNA vaccine encoding an EDIII-NS1 consensus design based on Indo-African sequences. Sankaradoss A, Jagtap S, Nazir J, Moula SE, Modak A, Fialho J, Iyer M, et al, (2022). Mol Ther. 7:S1525-0016(22)00013-2. doi: 10.1016/j.ymthe.2022.01.013.
11. Exploring the Medicinally Important Secondary Metabolites Landscape Through the Lens of Transcriptome Data in Fenugreek (Trigonella foenum graecum L.). Naika MB, Sathyanarayanan N, Sajeevan RS, Bhattacharyya T, Ghosh P, Meenakshi IS, et al (2022). Sci Rep 12, 13534. doi: 10.1038/s41598-022-17779-8.
12. A census of actin-associated proteins in humans. Meenakshi S I, Rao M, Mayor S and Sowdhamini R (2023) Front. Cell Dev. Biol. 11:1168050. doi: 10.3389/fcell.2023.1168050.
13. GenDiS3 database: census on the prevalence of protein domain superfamilies of known structure in the entire sequence database. S Joshi, S Mohapatra, D Kumar, A Joshi, M Iyer, R Sowdhamini. Database 2025, baaf035, doi: 10.1093/database/baaf035
Active flows drive clustering and sorting of membrane components with differential affinity to dynamic actin cytoskeleton. Bhat A, Das A, Iyer M, Beri S, Talluri S, Koester D, Rao M, Mayor S. bioRxiv. 2025 Aug 31:2025-08.
Books Published
Book chapter: Evolutionary Analysis of A Few Protein Superfamilies in Ocimum tenuiflorum in the book, The Ocimum Genome. Gandhimathi A., Nitish Sathyanarayanan, Meenakshi Iyer, Rachit Gupta and R. Sowdhamini., 2018. (Eds. Sashany A.K. and Kole C.) DOI:10.1007/978-3-319-97430-9
Linkedin Profile Link
https://www.linkedin.com/in/meenakshi-iyer-a4a38954
Google Scholar Link
https://scholar.google.com/citations?user=IVkcvqQAAAAJ&hl=en
ORCID ID Link
https://orcid.org/0000-0002-0488-7193
Scopus ID Link
https://www.scopus.com/authid/detail.uri?authorId=58245455600
Vidwan ID Link
