PhD Programs

Faculty of Pharmacy

Ph.D program Faculty of Pharmacy

Program Overview

The School of Pharmacy, MIT WPU has advanced research laboratories that facilitates great research outcome. The research guides are highly experienced with immense research and development track records. The management implicates the importance of research in meeting societal challenges and thus encourages freedom with conducive environment.

Grants: National research granting agencies including, DBT, (Nano-biotechnology), DST (FIST and Nano-mission), CSIR, etc. has funded our academic researchers extensively.

We offer industrial consultancy and has successfully implemented multiple projects.
PhD students often work with international collaborators for PhD work.

Research Areas

School is approved by the Pharmacy Council of India, New Delhi and All India Council of Technical Education, New Delhi.

PhD scholars will get opportunity to work in following research areas

Research focus is on the priority areas such as diabetes, cancer, standardization of Ayurveda formulations, Food-drug interaction and food-food interaction

  • Cyclodextrin Technology

  • Drug Design, Synthesis and biological evaluation of molecules

  • Development of various herbal formulations

  • Development and Validation of Analytical method development

  • Advanced drug delivery systems

  • Targeted anti-cancer nano-conjugates for the cellular studies

  • Cell regeneration and proliferation studies

  • Cellular morphology dynamics and kinetics

  • Targeted nano-robots for enhanced anti-cancer activity

  • Standardization of traditional medicines

  • Nutraceuticals

  • Extraction, isolation and separation of chemical constituents from herbal drugs

  • Development of Novel Drug Delivery System (NDDS) for herbal drugs

  • Development of stable Ayurvedic formulations

  • Preclinical and clinical study of natural drugs

  • Food drug interactions

  • The search of active components from plants used in Ayurveda to understand the validity of centuries old use of herbal medicines which possess anticancer, anti-inflammatory activity and antidiabetic activity.

  • Drug design and development

  • Organic reaction optimization and evaluation of pharmacological activities of molecules like anti-cancer, anti-microbial, analgesics, anti-inflammatory and so on.

  • Nanotechnology using organic chemistry

  • Solubility enhancement techniques

  • Prodrug design and evaluation

  • Analytical method development

  • Targeted Drug Delivery Systems (TDDS)

  • Nano-medicines

  • Transdermal drug delivery systems

  • Formulation & development of dosage forms

  • Solubility enhancement techniques

  • Optimization of drug products and of processes, especially Ayurvedic medicines

  • Application of systems biology to immunomodulator Ayurvedic medicines with an emphasis on cell signaling pathways and cell line studies

  • Isolation of phytoconstituents and herbal standardizations

  • Study of Metal oxide nanoparticles, nanocomposite for applications such as antidiabetic, antibacterial, antioxidant, etc

  • Antidiabetic activity evaluation, drug-drug interactions

  • Synthesis and evaluation of conjugates

  • Analytical method development and validations

  • Novel Drug Delivery System, Generic and Branded Drug product development

  • Development of parenterals, solids, semi solids and liquid dosage forms

  • Quality by design (QbD)

  • Drug delivery – conceptualization to product development

  • Development of Ayurvedic polyherbal formulations

  • Standardization of Indian Medicinal plants

  • Preparation of standardized extract of herbal drugs and isolation of phytoconstituents

  • Pharmacological screening and toxicity evaluation of polyherbal formulations, standardized extracts and phytoconstituents in laboratory animals

  • Drug interactions

  • Standardization of traditional medicines

  • Herbal dietary supplements and nutraceuticals

  • Extraction, isolation of phytochemicals from herbal drugs

  • Phytochemical screening

  • Plant tissue culture

  • Development of Novel Drug Delivery System for bulk preparation of Ayurvedic formulation

  • Herbal cosmetics method development

  • Study of Ayurveda with relevance to modern science technique.

  • Development of stable Ayurvedic formulations

PhD scholars will get opportunity to work in

i. Multidisciplinary research approach

ii. National and international collaborators

iii. Industrial funded research projects

iv. Scholars can opt for the stipend through sponsored research projects

State of the art laboratory facilities

Synthetic Chemistry laboratory: School of Pharmacy has a laboratory routinely involved in synthesis and characterization of drugs. Instruments essential for the research in synthetic drug discovery, NDDS and characterization are available.

 

Pilot plant: School has a well-equipped pilot plant for formulation and development of various oral dosage forms. The pilot plant is a prototype of a small scale pharmaceutical manufacturing facility which includes all departments such as tablets, capsules, ointments, creams and liquid orals.

 

Herbal and Alternative Medicines laboratory: School has a dedicated laboratory for research work on herbal and alternative medicines equipped with facilities for research on herbals, extracts and phytomedicines. Extractions and isolation of phytoconstituents, development of herbal formulations, development of herbal cosmetics, standardization of herbal & Ayurvedic medicines are routinely performed in this laboratory.

 

Analytical laboratory: The analytical laboratory of the school is equipped with advanced analytical instruments such as HPLC, flash-chromatography, FTIR, etc. This laboratory is commonly used by research students for analytical method development and bioanalytical studies.

 

Cell Biology and Cancer Research laboratory: The Cell Biology and Cancer Research laboratory of the school is well equipped with modern facilities and infrastructure to conduct high quality research. Research activities of the laboratory have resulted in many high impact factor publications, patents and technology transfer of innovative technologies to the industry.

Cover page articles:

https://pubs.rsc.org/en/content/articlelanding/2020/tb/c9tb02744k#!divAbstract

https://onlinelibrary.wiley.com/doi/10.1002/admi.201770019

 

Animal house facility: The animal house facility of the school has been approved by long from (CPCSEA), New Delhi for research on small animals. This facility is well-equipped with essential instruments such as metabolic cages, biochemistry analyzer, hematoanalyzer, Plate reader, Deep Fridge, cold-centrifuge, tissue homogenizer, etc.

International/National collaboration for research in School of Pharmacy

  • Freie’ University, Berlin, Germany.

  • North Dakota State University, USA.

  • Czech University of Life sciences, Prague.

  • CSIR-National Chemical Laboratory, Pune.

  • MIMER Medical College and Dental Hospital, Pune.

  • Department of Chemistry, Savitribai Phule Pune University, Pune.

  • School of Health Sciences, Savitribai Phule Pune University, Pune.

  • BVG Life Sciences, Pune.

  • Murli-Krishna Pharma, Pune

  • Sava Healthcare Pvt. Ltd., Pune

  • Actorius Innovation & Research, USA and Pune

  • PRADO Pvt. Ltd., Pune

Funding, consultancy, Patents, IPR from School of Pharmacy

  • Funding: 1.82 Cr from funding agencies such as CSIR, AICTE, DST and DBT.

  • Consultancy: 15 projects

  • Patents: 8 (Published)

Visit School of Pharmacy website for details,

https://mitwpu.edu.in/school-of-pharmacy/

Ph.D. Admission related queries, contact :

Dr. Anil Pawar
PhD coordinator
School of Pharmacy
anil.pawar@mitwpu.edu.in