1. Pharmaceutical Chemistry

Pharmaceutical Chemistry is the study of the molecular and mechanistic aspects of pharmaceuticals. The discipline emphasizes the chemistry of drug design and development, drug action, drug transport, drug delivery, and targeting. The development of new pharmaceuticals is critically dependent on a molecular-level understanding of biological processes and mechanisms of drug action. Progress in the field now depends on the design and synthesis of new molecules using tools such as structure activity relationships, combinatorial chemistry, and computer-aided drug design. In recent years rational design of drugs tuned to specific target sites is becoming a reality due to concurrent advances in chemistry and biology, including elucidation of the human genome. Chemists continue to be at the forefront of drug design, synthesis, testing, and development. Pharmaceutical Chemistry will emphasize the molecular basis underlying the creation of new drugs and health applications of bioactive compounds.


Pharmaceutics is the study and design of drug formulation for optimum delivery, stability, pharmacokinetics, and patient acceptance. Pharmaceutics is the discipline of pharmacy that deals with the process of turning a new chemical entity (NCE) into a medication to be used safely and effectively by patients. It is also called the science of dosage form design. There are many chemicals with pharmacological properties, but need special measures to help them achieve therapeutically relevant amounts at their sites of action. Pharmaceutics helps relate the formulation of drugs to their delivery and disposition in the body. Pharmaceutics deals with the formulation of a pure drug substance into a dosage form. Pharmaceutics is the study of chemical moieties designed to make them the so called chemical moiety after undergoing clinical trials might be formulated into various dosage forms after thoroughly studying the toxic profiles. The preformulation studies leads to unit-operations and the chemical moiety is further designed into various compounding products, extemporaneous preparations and formulations leading to Novel drug delivery systems such as transdermal patches, microspheres, Nano particles, liposomes etc. The stability of products is tested at two levels- Improvers and end product. Various microbiological testing for bacterial, virus and fungus are also done. The various pharmacokinetic and pharmacodynamics aspects of the dosage form are determined to conclude on the dosage regimen. It also includes Drug Regulatory affairs which assures proper manufacturing, packing, sale and distribution of the drug through the licensed authority only.

3.Pharmacognosy Phytochemistry

“Pharmacognosy” derives from two Greek words, “pharmakon”or drug, and “gnosis” or knowledge. Thus, Pharmacognosy (chemistry and biology of natural products) is the study of natural substances found in terrestrial and marine organisms (plants, animals, or microbes). Pharmacognosy has undergone significant change in recent years and today represents a highly interdisciplinary science which is one of five major areas of pharmaceutical education.

Research in Pharmacognosy

Despite convincing progress in Synthetic Chemistry, plants are the most important sources for preventive and curative medical preparations. WHO has estimated that at least 80% of all the global inhabitants rely on curative medical systems of medicine for their primary health needs and these systems are largely plant based. Research in Pharmacognosy is important because it leads new types of therapeutic moiety; increased understanding of the pharmacological, ecological and biochemical roles of molecules produced by nature; information on herbal medicines; and new methods for the analysis of drugs and herbal formulations. Research in the department of Pharmacognosy focused on analysis of medicinal plants including isolation, purification, identification and structure determination of bioactive substances from plant sources. The major research interests of department include:

    • Extraction, isolation and purification of medicinal plants.

    • Pharmacognostical and phytochemical studies of some selected medicinal plants.

    • Studies on herbal cosmetics.

    • Development of stable herbal formulation/Ayurvedic preparation.

    • Standardization of traditional formulations

    • Nutraceuticals

    • Plant tissue culture.


The word Pharmacology is derived Greek words Pharmakon (drug) and logos (study). Thus, Pharmacology is the study of drugs. It involves the study of the actions of drugs on cells, tissues and the whole body. Pharmacological studies include study of sources of drugs; their absorption, distribution, metabolism and excretion; their mechanism of action and drug toxicity. The aim of Pharmacology studies is to improve the way drugs are tested and to give greater benefit in the treatment of disease.

5. Quality Assurance Technique (QAT)

    • Introduction: Basic need of any business is to satisfy the customers, which is rationally possible only through quality services and products; therefore quality should be built in the product. Central role of Quality Assurance (QA) is to assure the quality through well planned activities and not just by testing the quality of final product. Quality Assurance act as caretaker of the Pharmaceutical Quality System (PQS) which are necessary to build quality in to the services and products which means QA is essential for better business plans and progression. QA work as gate keeper of Quality of Pharmaceuticals with deep understanding of all stages of product design and development (F&D), analytical development (ADL), manufacturing operations (GMP), process validation & controls, etc 1,

    • Quality Assurance is the action of giving proof required to set up quality in work, required for all those planned or systematic actions essential to provide sufficient assurance that a product or service will fulfill the offered requirements for quality. Quality Assurance presents the guidelines which are ‘fit for function’ and ‘do it right the first time’. It can be obtained by presenting suitable standards and standard operating procedures (SOPs) in-house

    • The pharmaceutical industry is the most regulated among all other industries. Each country has well established drug regulatory authorities controlling all regulatory aspects (research, manufacturing, transport, sales, safe disposal, etc.) of pharmaceuticals, medical devices and diagnostics and other health care needs viz. specialized foods articles and dietary supplements, etc

    • In the globalized era and increased export-import (Exim) trade, health care articles moving internationally needs to comply standards of all the nations involved in Exim operations. QA plays pivotal role in meeting compliance to the regulations and standards. QA personals play central role to ensure that National (viz. USFDA, TGA, MHRA, etc.) regional (ASEAN, CIS, GCC, PANDRH, ENVISA, etc.) and global (WHO, ICH, PICs, etc.) regulations relevant to the concerned product are complied. In nutshell Pharmaceutical Quality Assurance section must ensure that the drug manufacturing process complies with government regulations and stringent manufacturing standards so that drugs are safe, effective and work as promised. National, regional and global regulatory authorities have their own set of regulations in the form of drug laws, good laboratory practice (GLP), good clinical practice (GCP), good manufacture practice (GMP), current GPM (cGMP), etc. combined together called GXPs. GXPs lay down requirements for high quality systems to ensure the availability of the pharmaceuticals with desired quality, purity, safety and efficacy. In this view QA personnel are playing very vital role in drugs, biologics, medical devices, diagnostics and other health care (specialized foods articles and dietary supplements) quality aspects as it is the only effective link among all the pharmaceutical organization sections such as production, packing, QC, R&D (F&D, ADL, bulk, etc.), purchase, sales, warehouse & logistics, regulatory affairs, etc. In short QA plays vital role for pharmaceutical organization for it to be anticipating organization rather than reactive to situations. This is also true in view of current trend of continues changes in the existing regulation and introduction of new one e. g. herbal technology related regulations (global herbal perspective) by EMEA (herbal) and USFDA (Botanicals) guidelines as well as chines herbal medicine (CHM) and Japanese herbal regulations 5-8 . Quality unit (QA and QC) in each organization is concerned with quality of the services and product to protect the interest of the manufacturer and the user. QA plays vial role in these activities as it is caretaker of the Pharmaceutical Quality System (PQS) i. e. Quality Management